Understanding the Root Causes of Depression

Post written by PHS Staff Writer on May 16, 2023
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**What Triggers Depression?**

Depression is a mental health condition affecting millions of people worldwide. According to the World Health Organization (WHO), over 264 million people of all ages are affected by depression globally. While it is a prevalent mental health condition, the exact causes of depression remain somewhat elusive.

This article will explore the various factors that can contribute to depression.

Factors Contributing to Depression

Genetics

Research indicates that genetics significantly influence the likelihood of developing depression. Studies suggest that if you have a close family member with depression, you are more likely to develop it as well.

Recent research has pinpointed specific genes that may elevate the risk of depression. One such gene is the serotonin transporter gene, which regulates serotonin levels in the brain. Serotonin is a neurotransmitter that plays a key role in mood regulation. An imbalance in serotonin levels can lead to depression.

Additionally, variations in the gene coding for the brain-derived neurotrophic factor (BDNF) protein are linked to an increased risk of depression. BDNF supports the survival and growth of neurons in the brain. Low levels of BDNF can contribute to depression.

Brain Chemistry

An imbalance of certain chemicals in the brain, such as serotonin, dopamine, and norepinephrine, also plays a significant role in depression. These neurotransmitters help regulate mood, and any imbalance can result in symptoms like sadness and hopelessness.

Life Events

Stressful life events such as divorce, job loss, or the death of a loved one can contribute significantly to depression. Studies show that individuals who encounter these life-altering events are more prone to develop depression compared to those who do not.

Medical Conditions

Chronic illnesses like cancer, diabetes, and heart disease can cause immense physical and emotional stress, which can ultimately lead to depression. Additionally, some medications prescribed to treat these illnesses may also cause depression as a side effect.

Substance Abuse

Alcohol and drug use can disrupt the chemical balance in the brain, leading to depressive symptoms. Social studies also reveal that individuals struggling with substance abuse may face financial and legal troubles, further exacerbating feelings of depression.

Social Factors

People experiencing social hardships such as poverty, isolation, or discrimination are at a higher risk of developing depression. Social support and empathy play crucial roles in the recovery of individuals falling under this category.

For more information about mental health and support services, visit Pro Health Support.

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