Understanding Common and Serious Side Effects of Myrbetriq

When managing overactive bladder (OAB) symptoms such as frequent urination and urgency, Myrbetriq (mirabegron) can provide relief. However, it’s important to be aware of the possible side effects associated with this medication.

What is Myrbetriq?

Myrbetriq, generically known as mirabegron, treats overactive bladder (OAB) symptoms. As a member of beta-3 adrenergic agonists, it works by relaxing bladder muscles, thus decreasing the frequency and urgency of urination, along with reducing urinary incontinence episodes seen in OAB patients.

Unlike other OAB medications that usually affect nerve signals, Myrbetriq specifically targets the beta-3 receptors in bladder muscles. This helps to increase bladder capacity and reduce sudden involuntary contractions that are typical of OAB.

Typically taken orally once a day, with or without food, Myrbetriq should be used as directed by a healthcare provider. Adhering to the prescribed dosage and instructions is crucial for optimal effectiveness and to minimize side effects.

Myrbetriq Side Effects

Common Side Effects

Upon starting Myrbetriq, you may encounter some common side effects, which are generally mild. These include headaches, slightly increased blood pressure, urinary tract infections (UTIs), and nausea. These effects often decrease as your body acclimates to the medication.

1. Headaches – Headaches are frequently reported by Myrbetriq users. They can vary from mild to severe and may be more frequent during the initial stages of treatment.
2. Increased Blood Pressure – Some individuals may experience a slight increase in blood pressure. Monitoring blood pressure regularly is essential, especially for those with a history of hypertension.
3. Urinary Tract Infections (UTIs) – Some users may develop UTIs characterized by painful urination, frequent urination, and lower abdominal discomfort.
4. Nausea – Nausea is another common side effect, particularly in the early stages of treatment, but it may lessen over time.

Serious Side Effects

In rare cases, Myrbetriq can cause severe side effects that necessitate immediate medical attention:

1. Allergic Reactions – Myrbetriq can occasionally trigger allergic reactions, with symptoms like rash, itching, swelling, dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
2. Cardiovascular Effects – Myrbetriq may affect heart rhythm, leading to palpitations or an irregular heartbeat. Individuals with pre-existing heart conditions should use Myrbetriq cautiously and under close medical supervision.
3. Liver Damage – Although rare, Myrbetriq has been linked to liver issues such as elevated liver enzymes and liver damage. Signs include jaundice (yellowing of the skin or eyes), dark urine, and chronic fatigue.

Myrbetriq Side Effects in the Elderly

The elderly may be more vulnerable to certain side effects of Myrbetriq due to age-related changes in metabolism and organ function. Possible side effects include constipation, UTIs, dry mouth, increased blood pressure, and dizziness. Increased risk of falls due to dizziness or decreased coordination is also a concern.

Why is Myrbetriq So Expensive?

Myrbetriq’s high cost can be attributed to several factors. First, the substantial research and development expenses incurred by pharmaceutical companies for new drug development are factored into the drug’s pricing. Secondly, patent protection grants the manufacturer exclusive rights to sell Myrbetriq for a set duration, enabling higher prices without generic competition.

Additionally, the complex manufacturing processes, along with the costs associated with clinical trials, regulatory approvals, and marketing, contribute to the high price. Furthermore, the lack of significant competition in the market for OAB medications can keep prices elevated.

Myrbetriq Alternatives

If Myrbetriq (mirabegron) isn’t suitable for you or if you prefer other treatment methods, several alternatives can effectively manage overactive bladder symptoms:

• Anticholinergic Medications: These drugs block signals causing bladder muscle contractions. Examples include oxybutynin (Ditropan), tolterodine (Detrol), solifenacin (Vesicare), and darifenacin (Enablex).
• Beta-3 Adrenergic Agonists: Similar to Myrbetriq, these medications target the beta-3 receptors in the bladder but may have different side effects. One example is vibegron.
• Behavioral Therapies: Techniques such as bladder training, pelvic floor exercises (Kegel exercises), and biofeedback can help improve bladder control and reduce urgency and frequency.
• Topical Estrogen Therapy: This treatment can help strengthen urinary tract tissues in postmenopausal women, improving OAB symptoms.
• Botulinum Toxin Injections: Botox injections into the bladder muscle can reduce urgency and frequency by relaxing the bladder, especially when other treatments have failed.

Takeaways

As you navigate OAB treatment with Myrbetriq, keep these insights in mind. Being informed about the medication and its potential side effects empowers you to manage your health effectively.

If you encounter any concerning symptoms, whether common or severe, don’t hesitate to consult your healthcare provider. Ensuring that your treatment plan aligns with your needs and well-being is crucial to effective management.