Tolterodine

Uses of Tolterodine

Tolterodine is a medicine used to treat symptoms of an overactive bladder. These can include:

• a sudden and urgent need to pee (urinary urgency)
• needing to pee more often than usual (urinary frequency)
• wetting yourself if you cannot make it to the loo in time (urinary incontinence)

It’s also used to treat bedwetting in children (nocturnal enuresis).

Tolterodine works by relaxing the muscles around your bladder. This means your bladder can hold more liquid and you do not need to pee as often or as urgently.

Precautions and Warnings

People who are allergic to any of the following should not take tolterodine.

• Detrol
• Detrol LA
• Tolterodine
• Fesoterodine
• Toviaz
• Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific tolterodine products they stock.

Do not take tolterodine if you have a condition called urinary retention.

Do not take tolterodine if you have delayed or slow emptying of your stomach, a condition called gastric retention.

Do not take tolterodine if you have narrow-angle glaucoma, a condition that causes increased pressure inside the eye.

Do not take tolterodine unless it has been prescribed to you by a healthcare provider. Take it as prescribed.

Do not share tolterodine with other people, even if they have the same condition as you. It may harm them.

Keep tolterodine out of the reach of children.

You can take tolterodine with or without food.

Tolterodine can cause blurry vision, dizziness, and drowsiness. Do not drive or do other activities that require clear vision or alertness until you know how tolterodine affects you.

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if tolterodine is right for you.

Tell your healthcare provider if you have any of the following.

• Kidney or liver problems
• Stomach or intestinal problems
• Problems peeing, a weak urine stream, or a blockage in your bladder
• Narrow-angle glaucoma
• Myasthenia gravis
• History or family history of a rare heart condition called QT prolongation (long QT syndrome)

Tolterodine may interact with other medicines and supplements. Before using tolterodine, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

It is not known if or how tolterodine could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.

It is not known if tolterodine passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.

Dosage

Usual Adult Dose for Urinary Incontinence:

Immediate release tablets:
-Initial dose: 2 mg orally 2 times a day
-Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability

Extended release capsules:
-Initial dose: 4 mg orally once a day
-Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability

Usual Adult Dose for Urinary Frequency:

Immediate release tablets:
-Initial dose: 2 mg orally 2 times a day
-Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability

Extended release capsules:
-Initial dose: 4 mg orally once a day
-Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability

Side Effects

Common side:

• dry mouth;
• dizziness;
• constipation;
• stomach pain; or
• headache.