Xarelto vs. Eliquis are two widely prescribed anticoagulant medications specifically aimed at preventing and treating blood clots. Grasping the distinctions between these two drugs can assist patients and healthcare providers in making well-informed choices about which medication is the most suitable.
Xarelto vs. Eliquis
Xarelto and Eliquis are categorized as direct oral anticoagulants (DOACs) that function by diminishing the activity of Factor Xa, a pivotal protein in the blood clotting mechanism. Both medications are prescribed for preventing stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), as well as for treating and preventing deep vein thrombosis (DVT) and pulmonary embolism (PE).
Efficacy Comparison Between Xarelto and Eliquis
Numerous clinical trials have assessed the efficacy of Xarelto and Eliquis in preventing stroke and systemic embolism in NVAF patients. Research indicates that both medications are equally effective in reducing the risk of stroke and systemic embolism, with Eliquis showing a lower risk of major bleeding incidents.
In terms of treating and preventing DVT and PE, both Xarelto and Eliquis have been found effective. One study highlighted that Xarelto was non-inferior to the standard treatment involving enoxaparin and a vitamin K antagonist for DVT, while Eliquis was comparable to enoxaparin followed by warfarin for treating DVT and PE.
Safety of Xarelto and Eliquis
Both Xarelto and Eliquis carry a bleeding risk, a potential complication inherent to all anticoagulant medications. Although the overall risk of bleeding with these drugs is low, patients must be vigilant for any bleeding signs and seek immediate medical attention if they encounter any unusual symptoms.
Regarding adverse effects, Xarelto has been linked to a higher risk of gastrointestinal bleeding, while Eliquis has been associated with increased chances of dyspepsia (indigestion) and nausea. Certain health conditions or risk factors may heighten patient susceptibility to these adverse effects.
Cost Comparison Between Xarelto and Eliquis
When it comes to pricing, Xarelto costs $189.99 (10mg x 50 tablets), $289.89 (15mg x 90 tablets), and $289.89 (20mg x 90 tablets). In contrast, Eliquis costs $119.99 (2.5mg x 180 tablets) and $119.99 (5mg x 180 tablets).
Choosing Between Xarelto and Eliquis
In selecting between Xarelto and Eliquis, healthcare providers consider multiple factors such as the patient’s age, kidney function, and other health conditions. They also take into account physician preferences and clinical practice guidelines. Patients should discuss these factors with their healthcare provider to ensure they receive the most appropriate medication for their unique needs.
Both Xarelto and Eliquis are potent anticoagulant medications capable of preventing and treating blood clots. While they share many commonalities, significant differences in efficacy, safety, cost, and availability exist. By understanding these nuances, patients and healthcare providers can make well-educated decisions regarding the best treatment option.