Leukemia is a cancer affecting the blood and bone marrow. Patients diagnosed with this disease need specialized treatments to control its progression. Tasigna is one such medication that has proven effective in treating certain types of leukemia, bringing hope and better outcomes for many patients.
Let’s explore more about Tasigna, its uses, costs, generic name, and important considerations such as its interaction with coffee.
What is Tasigna?
Tasigna (generic name: nilotinib) is a medication prescribed for treating Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in adults. It falls under the category of tyrosine kinase inhibitors, which work by blocking the abnormal protein that signals cancer cells to grow, helping to prevent the spread of cancer cells.
Uses of Tasigna
Tasigna is used for:
- Treatment of Ph+ CML in the chronic phase: It is used in patients who are newly diagnosed or who did not respond well to other treatments.
- Treatment of Ph+ CML in the accelerated phase: It is also used when the disease has progressed from the chronic phase but hasn’t reached the blast phase yet.
Tasigna Dosage
The recommended dosage of Tasigna can vary based on the phase of chronic myeloid leukemia and the patient’s overall health. Typically, the dosage is as follows:
- For newly diagnosed Ph+ CML in the chronic phase: 300 mg taken twice daily.
- For chronic and accelerated phase Ph+ CML that shows resistance or intolerance to prior therapy: 400 mg taken twice daily.
Tasigna should not be taken on an empty stomach. Make sure to take the medication at least one hour before or two hours after a meal. Swallow the capsules whole with water, without breaking, chewing, or opening them.
Tasigna and Coffee
An important consideration for patients taking Tasigna is its interaction with certain foods and drinks. Specifically, Tasigna and coffee can interact, as coffee may influence the medication’s absorption. Patients are advised to avoid coffee and other caffeinated beverages close to their dosing times to ensure the medication’s full efficacy.
Tasigna Cost
The cost for Tasigna oral capsules (150 mg) is roughly $5,285 for a 28-capsule supply, though this can vary based on the pharmacy. These prices are for cash payments and do not apply to insurance holders, making it a significant financial factor for many patients. It’s essential for patients to talk to their healthcare provider or pharmacist about potential cost-saving options, including generic alternatives or financial assistance programs.
Tasigna Generic Name and Availability
Tasigna’s generic name is nilotinib. On January 5, 2024, a notable milestone was achieved when the U.S. Food and Drug Administration (FDA) approved a generic version of Tasigna.
Takeaways
Tasigna is a crucial medication for treating specific types of leukemia, providing hope for patients with Ph+ CML. Understanding its complete prescribing information, including the correct dosage, potential interactions like those with coffee, and the cost, is critical for effective treatment.
By staying informed and proactive about their treatment, patients can better manage their condition and work towards achieving the best possible outcomes with Tasigna.
Frequently Asked Questions (FAQs)
What should I do if I miss a dose?
If you miss a dose of Tasigna, take it as soon as you remember unless it is within 12 hours of your next dose. Do not take two doses at the same time to make up for the missed dose. You may skip the dose you missed and then continue with your regular dosing schedule.
Can I take other medications while on Tasigna?
It is important to be aware that certain medications may interact with Tasigna, potentially affecting its effectiveness or increasing the chances of experiencing adverse effects. Before initiating Tasigna treatment, always make sure to disclose to your healthcare provider all other drugs, supplements, or herbal medications you have.
What should I discuss with my healthcare provider before starting Tasigna?
Before starting Tasigna, discuss your medical history with your healthcare provider, especially if you have a history of heart problems, liver disease, or any other significant health conditions. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.